7KQN
Ternary complex of TERT (telomerase reverse transcriptase) with RNA template, DNA primer, an incoming dGTP and a downstream hybrid duplex
Summary for 7KQN
Entry DOI | 10.2210/pdb7kqn/pdb |
Descriptor | Telomerase reverse transcriptase, RNA (5'-R(*CP*AP*AP*AP*GP*AP*AP*AP*UP*CP*CP*AP*GP*GP*UP*GP*CP*A)-3'), DNA (5'-D(*GP*CP*AP*CP*CP*TP*G)-3'), ... (10 entities in total) |
Functional Keywords | rap, repeat addition processivity, dna hairpin, rna template, telomere, tbe, template-boundary element, transferase, transferase-rna-dna complex, transferase/rna/dna |
Biological source | Tribolium castaneum (red flour beetle) More |
Total number of polymer chains | 8 |
Total formula weight | 164168.83 |
Authors | Choi, W.S.,Weng, P.J.,Yang, W. (deposition date: 2020-11-17, release date: 2022-03-23, Last modification date: 2023-10-18) |
Primary citation | Choi, W.S.,Weng, P.J.,Yang, W. Flexibility of telomerase in binding the RNA template and DNA telomeric repeat. Proc.Natl.Acad.Sci.USA, 119:-, 2022 Cited by PubMed: 34969861DOI: 10.1073/pnas.2116159118 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.02 Å) |
Structure validation
Download full validation report