7KNU

CryoEM structure of the CGRP receptor with bound CGRP peptide in a detergent micelle

Summary for 7KNU

• Entry DOI: 10.2210/pdb7knu/pdb
• Related: 6E3Y
• EMDB information: 22963
• Descriptor: Receptor activity-modifying protein 1, Calcitonin gene-related peptide 1, Calcitonin gene-related peptide type 1 receptor (3 entities in total)
• Functional Keywords: gpcr, cgrp receptor, membrane protein, signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 77138.57

Authors

Belousoff, M.J.,Danev, R. (deposition date: 2020-11-06, release date: 2021-02-24, Last modification date: 2021-04-21)

• Primary citation: Josephs, T.M.,Belousoff, M.J.,Liang, Y.L.,Piper, S.J.,Cao, J.,Garama, D.J.,Leach, K.,Gregory, K.J.,Christopoulos, A.,Hay, D.L.,Danev, R.,Wootten, D.,Sexton, P.M.; Structure and dynamics of the CGRP receptor in apo and peptide-bound forms.; Science, 372:-, 2021; PubMed: 33602864; DOI: 10.1126/science.abf7258

Experimental method

ELECTRON MICROSCOPY (3.49 Å)