7KMR
Crystal structure analysis of human KRAS mutant
Summary for 7KMR
Entry DOI | 10.2210/pdb7kmr/pdb |
Descriptor | Isoform 2B of GTPase KRas, GUANOSINE-5'-DIPHOSPHATE (3 entities in total) |
Functional Keywords | hydrolase, gtpase, oncogenic |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 24146.99 |
Authors | Seo, H.-S.,Dhe-Paganon, S. (deposition date: 2020-11-03, release date: 2021-11-10, Last modification date: 2023-10-18) |
Primary citation | Johnson, C.W.,Seo, H.S.,Terrell, E.M.,Yang, M.H.,KleinJan, F.,Gebregiworgis, T.,Gasmi-Seabrook, G.M.C.,Geffken, E.A.,Lakhani, J.,Song, K.,Bashyal, P.,Popow, O.,Paulo, J.A.,Liu, A.,Mattos, C.,Marshall, C.B.,Ikura, M.,Morrison, D.K.,Dhe-Paganon, S.,Haigis, K.M. Regulation of GTPase function by autophosphorylation. Mol.Cell, 82:950-968.e14, 2022 Cited by PubMed: 35202574DOI: 10.1016/j.molcel.2022.02.011 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.51 Å) |
Structure validation
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