7KME

CRYSTAL STRUCTURE OF HUMAN ALPHA-THROMBIN INHIBITED WITH SEL2711.

Summary for 7KME
Related PRD IDPRD_000257
DescriptorTHROMBIN L-CHAIN, THROMBIN H-CHAIN, HIRUGEN, ... (6 entities in total)
Functional Keywordsselectide inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (human)
More
Cellular locationSecreted, extracellular space: P00734 P00734
Total number of polymer chains4
Total formula weight36030.07
Authors
Mochalkin, I.,Tulinsky, A. (deposition date: 1999-02-26, release date: 1999-03-09, Last modification date: 2017-10-04)
Primary citationMochalkin, I.,Tulinsky, A.
Structures of thrombin retro-inhibited with SEL2711 and SEL2770 as they relate to factor Xa binding.
Acta Crystallogr.,Sect.D, 55:785-793, 1999
PubMed: 10089309
DOI: 110.1107/S0907444999000359
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation
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PDB entries from 2021-06-16