7KME
CRYSTAL STRUCTURE OF HUMAN ALPHA-THROMBIN INHIBITED WITH SEL2711.
Summary for 7KME
| Entry DOI | 10.2210/pdb7kme/pdb |
| Related PRD ID | PRD_000257 |
| Descriptor | THROMBIN L-CHAIN, THROMBIN H-CHAIN, HIRUGEN, ... (6 entities in total) |
| Functional Keywords | selectide inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Homo sapiens (human) More |
| Cellular location | Secreted, extracellular space: P00734 P00734 |
| Total number of polymer chains | 4 |
| Total formula weight | 36030.07 |
| Authors | Mochalkin, I.,Tulinsky, A. (deposition date: 1999-02-26, release date: 1999-03-09, Last modification date: 2023-11-15) |
| Primary citation | Mochalkin, I.,Tulinsky, A. Structures of thrombin retro-inhibited with SEL2711 and SEL2770 as they relate to factor Xa binding. Acta Crystallogr.,Sect.D, 55:785-793, 1999 Cited by PubMed: 10089309DOI: 10.1107/S0907444999000359 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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