7KLD

Crystal Structure of an Essential Ribosomal Processing Protease Prp from S. aureus in complex with a covalently linked product Peptide

Summary for 7KLD

Entry DOI	10.2210/pdb7kld/pdb
Related PRD ID	PRD_002454
Descriptor	Phage-related ribosomal protease, LYS-LEU-ASN-LEU-GLN-PHE-PCS, CALCIUM ION, ... (4 entities in total)
Functional Keywords	cysteine protease ribosomal protein l27, hydrolase, product complex
Biological source	Staphylococcus aureus More
Total number of polymer chains	6
Total formula weight	38253.80
Authors	Wright, H.T.,Peterson, D. (deposition date: 2020-10-29, release date: 2021-09-01, Last modification date: 2023-10-25)
Primary citation	Hotinger, J.A.,Pendergrass, H.A.,Peterson, D.,Wright, H.T.,May, A.E. Phage-Related Ribosomal Protease (Prp) of Staphylococcus aureus : In Vitro Michaelis-Menten Kinetics, Screening for Inhibitors, and Crystal Structure of a Covalent Inhibition Product Complex. Biochemistry, 61:1323-1336, 2022 Cited by PubMed: 35731716 DOI: 10.1021/acs.biochem.2c00010 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation