7UIS
Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B(S1303D)
Replaces: 7KL4Summary for 7UIS
Entry DOI | 10.2210/pdb7uis/pdb |
Related | 6XOE |
Descriptor | Calcium/calmodulin-dependent protein kinase type II subunit alpha, Glutamate receptor ionotropic, NMDA 2B (2 entities in total) |
Functional Keywords | camkii, kinase, human, camk2a, transferase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 33330.25 |
Authors | Ozden, C.,Stratton, M.M.,Garman, S.C. (deposition date: 2022-03-29, release date: 2022-04-06, Last modification date: 2023-10-18) |
Primary citation | Ozden, C.,Sloutsky, R.,Mitsugi, T.,Santos, N.,Agnello, E.,Gaubitz, C.,Foster, J.,Lapinskas, E.,Esposito, E.A.,Saneyoshi, T.,Kelch, B.A.,Garman, S.C.,Hayashi, Y.,Stratton, M.M. CaMKII binds both substrates and activators at the active site. Cell Rep, 40:111064-111064, 2022 Cited by PubMed: 35830796DOI: 10.1016/j.celrep.2022.111064 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.58 Å) |
Structure validation
Download full validation report