7KHO
NicA2 variant N462V in complex with (S)-nicotine
Summary for 7KHO
Entry DOI | 10.2210/pdb7kho/pdb |
Related | 7KHN |
Descriptor | Amine oxidase, (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE, FLAVIN-ADENINE DINUCLEOTIDE, ... (4 entities in total) |
Functional Keywords | flavoenzyme, oxidoreductase, nicotine, rossmann-core fold, flavoprotein |
Biological source | Pseudomonas putida S16 |
Total number of polymer chains | 4 |
Total formula weight | 218392.82 |
Authors | Tararina, M.A.,Allen, K.N. (deposition date: 2020-10-21, release date: 2021-02-10, Last modification date: 2023-10-18) |
Primary citation | Tararina, M.A.,Dam, K.K.,Dhingra, M.,Janda, K.D.,Palfey, B.A.,Allen, K.N. Fast Kinetics Reveals Rate-Limiting Oxidation and the Role of the Aromatic Cage in the Mechanism of the Nicotine-Degrading Enzyme NicA2. Biochemistry, 60:259-273, 2021 Cited by PubMed: 33464876DOI: 10.1021/acs.biochem.0c00855 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.69 Å) |
Structure validation
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