7KHO

NicA2 variant N462V in complex with (S)-nicotine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Amine oxidase	polymer	490	53650.4	4	UniProt (F8G0P2) Pfam (PF01593)	Pseudomonas putida S16
2	E, G, I, K (A, B, C, D)	(S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE	non-polymer		162.2	4	Chemie (NCT)
3	F, H, J, L (A, B, C, D)	FLAVIN-ADENINE DINUCLEOTIDE	non-polymer		785.5	4	Chemie (FAD)
4	M, N, O (A, B, C)	water	water		18.0	17	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 482 (UniProt: F8G0P2)

PDB	External Database	Details
Val 462	Asn 462	engineered mutation
Leu 483	-	expression tag
Glu 484	-	expression tag
His 485	-	expression tag
His 486	-	expression tag
His 487	-	expression tag
His 488	-	expression tag
His 489	-	expression tag
His 490	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	214601.7
Non-Polymers*	Number of molecules	8
	Total formula weight	3791.1
All*	Total formula weight	218392.8

*Water molecules are not included.