7KH4
Dihydrodipicolinate synthase (DHDPS) from C.jejuni, H56W mutant with pyruvate bound in the active site and R,R-bislysine bound at the allosteric site
Summary for 7KH4
Entry DOI | 10.2210/pdb7kh4/pdb |
Descriptor | 4-hydroxy-tetrahydrodipicolinate synthase, (2R,5R)-2,5-diamino-2,5-bis(4-aminobutyl)hexanedioic acid, MAGNESIUM ION, ... (10 entities in total) |
Functional Keywords | dihydrodipicolinate synthase, lyase |
Biological source | Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) |
Total number of polymer chains | 6 |
Total formula weight | 212552.11 |
Authors | Saran, S.,Majdi Yazdi, M.,Sanders, D.A.R. (deposition date: 2020-10-19, release date: 2021-10-27, Last modification date: 2023-11-29) |
Primary citation | Majdi Yazd, M.,Reddy Annadi, K.,Saran, S.,Bhagwat, A.,Sanders, D.A.R.,Palmer, D.R.J. Fluorescence-based Assay Development for Screening Novel Inhibitors of Dihydrodipicolinate Synthase from Campylobacter jejuni To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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