7KFZ

Structure of a ternary KRas(G13D)-SOS complex

Summary for 7KFZ

Entry DOI	10.2210/pdb7kfz/pdb
EMDB information	22857
Descriptor	GTPase KRas, Son of sevenless homolog 1, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... (4 entities in total)
Functional Keywords	ras, sos, gtpase, hydrolase-signaling protein complex, hydrolase/signaling protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	3
Total formula weight	96769.89
Authors	Liu, C.,Moghadamchargari, Z.,Laganowsky, A.,Zhao, M. (deposition date: 2020-10-15, release date: 2021-03-31, Last modification date: 2024-03-06)
Primary citation	Moghadamchargari, Z.,Shirzadeh, M.,Liu, C.,Schrecke, S.,Packianathan, C.,Russell, D.H.,Zhao, M.,Laganowsky, A. Molecular assemblies of the catalytic domain of SOS with KRas and oncogenic mutants. Proc.Natl.Acad.Sci.USA, 118:-, 2021 Cited by PubMed: 33723061 DOI: 10.1073/pnas.2022403118 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.47 Å)

Structure validation