7KFZ
Structure of a ternary KRas(G13D)-SOS complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | GTPase KRas | polymer | 170 | 19386.8 | 2 | UniProt (P01116) Pfam (PF00071) | Homo sapiens (Human) | K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras |
| 2 | B (B) | Son of sevenless homolog 1 | polymer | 491 | 57449.7 | 1 | UniProt (Q07889) Pfam (PF00618) Pfam (PF00617) | Homo sapiens (Human) | SOS-1 |
| 3 | D (C) | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 1 | Chemie (GNP) | |||
| 4 | E (C) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) |
Sequence modifications
A, C: 1 - 169 (UniProt: P01116)
B: 564 - 1049 (UniProt: Q07889)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Asp 13 | Gly 13 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 559 | - | expression tag |
| Ala 560 | - | expression tag |
| Met 561 | - | expression tag |
| Gly 562 | - | expression tag |
| Ser 563 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 96223.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 546.5 | |
| All* | Total formula weight | 96769.9 |
