7KFY

Structural basis for a germline-biased antibody response to SARS-CoV-2 (RBD:C1A-F10 Fab)

7KFY の概要

• エントリーDOI: 10.2210/pdb7kfy/pdb
• 関連するPDBエントリー: 7KFV 7KFW 7KFX
• 分子名称: Spike glycoprotein, heavy chain of human antibody C1A-F10 Fab, light chain of human antibody C1A-F10 Fab, ... (5 entities in total)
• 機能のキーワード: covid-19, sars-cov-2, neutralizing antibody, affinity maturation, immune system, immune system-viral protein complex, immune system/viral protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 72791.25

構造登録者

Pan, J.,Abraham, J.,Clark, L.,Clark, S. (登録日: 2020-10-15, 公開日: 2020-12-02, 最終更新日: 2023-10-18)

• 主引用文献: Clark, S.A.,Clark, L.E.,Pan, J.,Coscia, A.,McKay, L.G.A.,Shankar, S.,Johnson, R.I.,Griffiths, A.,Abraham, J.; Molecular basis for a germline-biased neutralizing antibody response to SARS-CoV-2.; Biorxiv, 2020; PubMed: 33200128; DOI: 10.1101/2020.11.13.381533

実験手法

X-RAY DIFFRACTION (2.157 Å)