7KBN
1.60 Angstrom resolution crystal structure of the beta-Q114A mutant of Tryptophan Synthase in complex with N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site, cesium ion at the metal coordination site, and 2-aminophenol quinonoid at the enzyme beta site
Summary for 7KBN
Entry DOI | 10.2210/pdb7kbn/pdb |
Related | 4HPJ 4KKX 6DUC 6O1H 6VFD 6XE3 |
Descriptor | Tryptophan synthase alpha chain, CESIUM ION, Tryptophan synthase beta chain, ... (11 entities in total) |
Functional Keywords | inhibitor, tryptophan synthase, lyase, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
Biological source | Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) More |
Total number of polymer chains | 2 |
Total formula weight | 75211.65 |
Authors | Hilario, E.,Dunn, M.F.,Mueller, L.J. (deposition date: 2020-10-02, release date: 2021-10-13, Last modification date: 2023-10-18) |
Primary citation | Hilario, E.,Dunn, M.F.,Mueller, L.J. 1.60 Angstrom resolution crystal structure of the beta-Q114A mutant of Tryptophan Synthase in complex with N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site, cesium ion at the metal coordination site, and 2-aminophenol quinonoid at the enzyme beta site. To be Published, |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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