7K9M

Crystal structure of the complex of M. tuberculosis PheRS with cognate precursor tRNA and 5'-O-(N-phenylalanyl)sulfamoyl-adenosine

7K9M の概要

• エントリーDOI: 10.2210/pdb7k9m/pdb
• 関連するPDBエントリー: 7K98 7KA0
• 分子名称: Phenylalanine--tRNA ligase alpha subunit, Phenylalanine--tRNA ligase beta subunit, tRNA(Phe), ... (9 entities in total)
• 機能のキーワード: aminoacylation, phenylalanyl trna synthetase, adenylate analog, ligase-rna complex, structural genomics, center for structural genomics of infectious diseases, csgid, ligase/rna
• 由来する生物種: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 152768.88

構造登録者

Michalska, K.,Chang, C.,Jedrzejczak, R.,Wower, J.,Baragana, B.,Forte, B.,Gilbert, I.H.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2020-09-29, 公開日: 2021-05-12, 最終更新日: 2023-10-18)

• 主引用文献: Michalska, K.,Jedrzejczak, R.,Wower, J.,Chang, C.,Baragana, B.,Gilbert, I.H.,Forte, B.,Joachimiak, A.; Mycobacterium tuberculosis Phe-tRNA synthetase: structural insights into tRNA recognition and aminoacylation.; Nucleic Acids Res., 49:5351-5368, 2021; PubMed: 33885823; DOI: 10.1093/nar/gkab272

実験手法

X-RAY DIFFRACTION (2.5 Å)