7K5E

1.75 A resolution structure of WT BfrB from Pseudomonas aeruginosa in complex with a protein-protein interaction inhibitor JAG-5-7

Summary for 7K5E

• Entry DOI: 10.2210/pdb7k5e/pdb
• Descriptor: Ferroxidase, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING FE, ... (5 entities in total)
• Functional Keywords: biofilms, electron transport, iron storage, iron binding, iron mobilization, protein-protein interaction inhibitor, oxidoreductase
• Biological source: Pseudomonas aeruginosa
• Total number of polymer chains: 12
• Total formula weight: 229684.78

Authors

Lovell, S.,Battaile, K.P.,Soldano, A.,Punchi-Hewage, A.,Meraz, K.,Annor-Gyamfi, J.K.,Yao, H.,Bunce, R.A.,Rivera, M. (deposition date: 2020-09-16, release date: 2020-12-16, Last modification date: 2023-10-18)

• Primary citation: Soldano, A.,Yao, H.,Punchi Hewage, A.N.D.,Meraz, K.,Annor-Gyamfi, J.K.,Bunce, R.A.,Battaile, K.P.,Lovell, S.,Rivera, M.; Small Molecule Inhibitors of the Bacterioferritin (BfrB)-Ferredoxin (Bfd) Complex Kill Biofilm-Embedded Pseudomonas aeruginosa Cells.; Acs Infect Dis., 7:123-140, 2021; PubMed: 33269912; DOI: 10.1021/acsinfecdis.0c00669

Experimental method

X-RAY DIFFRACTION (1.75 Å)