7K4A
Cryo-EM structure of human TRPV6 in the open state
Summary for 7K4A
Entry DOI | 10.2210/pdb7k4a/pdb |
EMDB information | 22662 |
Descriptor | Transient receptor potential cation channel subfamily V member 6, CHOLESTEROL HEMISUCCINATE, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... (4 entities in total) |
Functional Keywords | trpv6, ion channel, open state, membrane protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 354898.30 |
Authors | Neuberger, A.,Nadezhdin, K.D.,Singh, A.K.,Sobolevsky, A.I. (deposition date: 2020-09-15, release date: 2020-12-09, Last modification date: 2024-03-06) |
Primary citation | Bhardwaj, R.,Lindinger, S.,Neuberger, A.,Nadezhdin, K.D.,Singh, A.K.,Cunha, M.R.,Derler, I.,Gyimesi, G.,Reymond, J.L.,Hediger, M.A.,Romanin, C.,Sobolevsky, A.I. Inactivation-mimicking block of the epithelial calcium channel TRPV6. Sci Adv, 6:-, 2020 Cited by PubMed: 33246965DOI: 10.1126/sciadv.abe1508 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.26 Å) |
Structure validation
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