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7K02

The crystal structure of a BAK dimer activated by detergent

Summary for 7K02
Entry DOI10.2210/pdb7k02/pdb
Related4U2V
DescriptorBcl-2 homologous antagonist/killer (1 entity in total)
Functional Keywordsbak, bh3-in-groove dimer, bcl-2 fold, pore forming, proapoptotic, apoptosis
Biological sourceHomo sapiens (Human)
Total number of polymer chains6
Total formula weight81602.37
Authors
Birkinshaw, R.W.,Czabotar, P.E. (deposition date: 2020-09-02, release date: 2021-03-31, Last modification date: 2023-10-18)
Primary citationBirkinshaw, R.W.,Iyer, S.,Lio, D.,Luo, C.S.,Brouwer, J.M.,Miller, M.S.,Robin, A.Y.,Uren, R.T.,Dewson, G.,Kluck, R.M.,Colman, P.M.,Czabotar, P.E.
Structure of detergent-activated BAK dimers derived from the inert monomer.
Mol.Cell, 81:2123-, 2021
Cited by
PubMed: 33794146
DOI: 10.1016/j.molcel.2021.03.014
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.4 Å)
Structure validation

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