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7JQW

The external aldimine crystal structure of Salmonella typhimurium Tryptophan Synthase mutant beta-S377A in complex with cesium ion at the metal coordination site. The single beta-Q114 rotamer conformation allows a hydrogen bond to form with the PLP oxygen at the position 3 in the ring

Summary for 7JQW
Entry DOI10.2210/pdb7jqw/pdb
Related6WDU 6XSY 7JMQ
DescriptorTryptophan synthase alpha chain, Tryptophan synthase beta chain, DIMETHYL SULFOXIDE, ... (10 entities in total)
Functional Keywordslyase, inhibitor complex, lyase-lyase inhibitor complex, lyase/lyase inhibitor
Biological sourceSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
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Total number of polymer chains2
Total formula weight74418.95
Authors
Hilario, E.,Dunn, M.F.,Mueller, L.J. (deposition date: 2020-08-11, release date: 2021-08-25, Last modification date: 2023-10-18)
Primary citationHilario, E.,Dunn, M.F.,Mueller, L.J.
The external aldimine crystal structure of Salmonella typhimurium Tryptophan Synthase mutant beta-S377A in complex with cesium ion at the metal coordination site. The single beta-Q114 rotamer conformation allows a hydrogen bond to form with the PLP oxygen at the position 3 in the ring.
To be Published,
Experimental method
X-RAY DIFFRACTION (1.7 Å)
Structure validation

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