7JNI
Crystal structure of the angiotensin II type 2 receptoror (AT2R) in complex with EMA401
Summary for 7JNI
Entry DOI | 10.2210/pdb7jni/pdb |
Descriptor | Soluble cytochrome b562,Type-2 angiotensin II receptor, Olodanrigan, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ... (7 entities in total) |
Functional Keywords | angiotensin ii type 2 receptor, at2r, ema401, pd-126055, g protein-coupled receptor, gpcr, bril fusion, glioblastoma, gbm, membrane protein, lcp |
Biological source | Escherichia coli More |
Total number of polymer chains | 2 |
Total formula weight | 96734.20 |
Authors | Cherezov, V.,Shaye, H.,Han, G.W. (deposition date: 2020-08-04, release date: 2022-02-09, Last modification date: 2023-10-18) |
Primary citation | Perryman, R.,Renziehausen, A.,Shaye, H.,Kostagianni, A.D.,Tsiailanis, A.D.,Thorne, T.,Chatziathanasiadou, M.V.,Sivolapenko, G.B.,El Mubarak, M.A.,Han, G.W.,Zarzycka, B.,Katritch, V.,Lebon, G.,Lo Nigro, C.,Lattanzio, L.,Morse, S.V.,Choi, J.J.,O'Neill, K.,Kanaki, Z.,Klinakis, A.,Crook, T.,Cherezov, V.,Tzakos, A.G.,Syed, N. Inhibition of the angiotensin II type 2 receptor AT 2 R is a novel therapeutic strategy for glioblastoma. Proc.Natl.Acad.Sci.USA, 119:e2116289119-e2116289119, 2022 Cited by PubMed: 35917342DOI: 10.1073/pnas.2116289119 PDB entries with the same primary citation |
Experimental method |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)