7JLL

The internal aldimine crystal structure of Salmonella typhimurium Tryptophan Synthase mutant beta-S377A in complex with inhibitor 2-({[4-(trifluoromethoxy)phenyl]sulfonyl}amino)ethyl dihydrogen phosphate (F9F) at the alpha-site, Cesium ion at the metal coordination site and L-Tryptophan at the enzyme beta-site

7JLL の概要

• エントリーDOI: 10.2210/pdb7jll/pdb
• 関連するPDBエントリー: 5CGQ 6XE3 6XSY 7JHW
• 分子名称: Tryptophan synthase alpha chain, 1,2-ETHANEDIOL, Tryptophan synthase beta chain, ... (11 entities in total)
• 機能のキーワード: lyase, inhibitor complex, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• 由来する生物種: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 76004.14

構造登録者

Hilario, E.,Dunn, M.F.,Mueller, L.J. (登録日: 2020-07-29, 公開日: 2021-08-04, 最終更新日: 2023-10-18)

• 主引用文献: Hilario, E.,Mueller, L.J.,Dunn, M.F.; The internal aldimine crystal structure of Salmonella typhimurium Tryptophan Synthase mutant beta-S377A in complex with inhibitor 2-({[4-(trifluoromethoxy)phenyl]sulfonyl}amino)ethyl dihydrogen phosphate (F9F) at the alpha-site, Cesium ion at the metal coordination site and L-Tryptophan at the enzyme beta-site.; To be Published,

実験手法

X-RAY DIFFRACTION (1.55 Å)