7JHW

The internal aldimine crystal structure of Salmonella typhimurium Tryptophan Synthase mutant beta-S377A in complex with inhibitor 2-({[4-(trifluoromethoxy)phenyl]sulfonyl}amino)ethyl dihydrogen phosphate (F9F) at the alpha-site and Cesium ion at the metal coordination site

7JHW の概要

• エントリーDOI: 10.2210/pdb7jhw/pdb
• 関連するPDBエントリー: 4HT3 4XUG 6C73
• 分子名称: Tryptophan synthase alpha chain, Tryptophan synthase beta chain, 2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE, ... (9 entities in total)
• 機能のキーワード: lyase, inhibitor complex, tryptophan synthase, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• 由来する生物種: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 74494.56

構造登録者

Hilario, E.,Mueller, L.J.,Dunn, M.F. (登録日: 2020-07-21, 公開日: 2021-07-28, 最終更新日: 2023-10-18)

• 主引用文献: Hilario, E.,Mueller, L.J.,Dunn, M.F.; The internal aldimine crystal structure of Salmonella typhimurium Tryptophan Synthase mutant beta-S377A in complex with inhibitor 2-({[4-(trifluoromethoxy)phenyl]sulfonyl}amino)ethyl dihydrogen phosphate (F9F) at the alpha-site and Cesium ion at the metal coordination site.; To be Published,

実験手法

X-RAY DIFFRACTION (1.65 Å)