7JHP
Crystal structure of HRas in complex with the Ras-binding and cysteine-rich domains of CRaf-kinase
Summary for 7JHP
Entry DOI | 10.2210/pdb7jhp/pdb |
Descriptor | GTPase HRas, RAF proto-oncogene serine/threonine-protein kinase, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... (6 entities in total) |
Functional Keywords | ras, raf, rbd, crd, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 34862.48 |
Authors | Cookis, T.,Mattos, C. (deposition date: 2020-07-21, release date: 2020-08-05, Last modification date: 2023-10-18) |
Primary citation | Cookis, T.,Mattos, C. Crystal Structure Reveals the Full Ras-Raf Interface and Advances Mechanistic Understanding of Raf Activation. Biomolecules, 11:-, 2021 Cited by PubMed: 34356620DOI: 10.3390/biom11070996 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.766 Å) |
Structure validation
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