7JHJ

Structure of the Epstein-Barr virus GPCR BILF1 in complex with human Gi

Summary for 7JHJ

• Entry DOI: 10.2210/pdb7jhj/pdb
• EMDB information: 22338
• Descriptor: Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
• Functional Keywords: membrane protein, viral gpcr, class a-like gpcr, epstein-barr virus
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 5
• Total formula weight: 148763.61

Authors

Tsutsumi, N.,Qu, Q.H.,Skiniotis, G.,Garcia, K.C. (deposition date: 2020-07-20, release date: 2021-07-07, Last modification date: 2021-07-28)

• Primary citation: Tsutsumi, N.,Qu, Q.,Mavri, M.,Baggesen, M.S.,Maeda, S.,Waghray, D.,Berg, C.,Kobilka, B.K.,Rosenkilde, M.M.,Skiniotis, G.,Garcia, K.C.; Structural basis for the constitutive activity and immunomodulatory properties of the Epstein-Barr virus-encoded G protein-coupled receptor BILF1.; Immunity, 54:1405-1416.e7, 2021; PubMed: 34216564; DOI: 10.1016/j.immuni.2021.06.001

Experimental method

ELECTRON MICROSCOPY (3.2 Å)