7JHJ
Structure of the Epstein-Barr virus GPCR BILF1 in complex with human Gi
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Guanine nucleotide-binding protein G(i) subunit alpha-1 | polymer | 353 | 40283.8 | 1 | UniProt (P63096) Pfam (PF00503) | Homo sapiens (Human) | Adenylate cyclase-inhibiting G alpha protein |
| 2 | B (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 345 | 37728.2 | 1 | UniProt (P62873) Pfam (PF25391) | Homo sapiens (Human) | Transducin beta chain 1 |
| 3 | C (C) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 67 | 7432.6 | 1 | UniProt (P59768) Pfam (PF00631) | Homo sapiens (Human) | G gamma-I |
| 4 | D (D) | Antibody fragment scFv16 | polymer | 256 | 27340.5 | 1 | Mus musculus (mouse) | ||
| 5 | E (R) | BILF1 | polymer | 321 | 35491.9 | 1 | UniProt (Q3KSP2) Pfam (PF25732) UniProt (by SIFTS) (P03208) | Epstein-Barr virus (HHV-4 Human herpesvirus 4) | BILF1 membrane protein,BILF1 protein,G protein-coupled receptor,Membrane protein,Probable membrane protein |
| 6 | F (R) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 1 | Chemie (Y01) PubChem (65082) PubChem (363416) PubChem (500055) PubChem (13301926) PubChem (13301927) PubChem (16219150) PubChem (22210610) PubChem (45489984) PubChem (57163942) PubChem (89891013) PubChem (99567468) PubChem (124427194) PubChem (124897021) PubChem (124897020) PubChem (10005657) PubChem (130340716) PubChem (11969853) PubChem (137392566) PubChem (137496323) PubChem (155804219) PubChem (169132514) PubChem (60078761) PubChem (73440805) PubChem (99567469) PubChem (124301053) PubChem (124302591) PubChem (124303794) PubChem (124421343) PubChem (124427195) PubChem (124914595) PubChem (124914596) PubChem (131705526) PubChem (137332121) PubChem (137496357) PubChem (146157332) PubChem (154929912) PubChem (155199678) PubChem (156327905) PubChem (156426247) PubChem (156516588) PubChem (166979870) PubChem (167024614) PubChem (169132513) PubChem (170117245) PubChem (172400028) |
Sequence modifications
B: 2 - 340 (UniProt: P62873)
R: 1 - 312 (UniProt: Q3KSP2)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Gly 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ala 313 | - | expression tag |
| Ala 314 | - | expression tag |
| Ala 315 | - | expression tag |
| Leu 316 | - | expression tag |
| Glu 317 | - | expression tag |
| Val 318 | - | expression tag |
| Leu 319 | - | expression tag |
| Phe 320 | - | expression tag |
| Gln 321 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 148276.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 486.7 | |
| All* | Total formula weight | 148763.6 |
