7JHJ
Structure of the Epstein-Barr virus GPCR BILF1 in complex with human Gi
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Guanine nucleotide-binding protein G(i) subunit alpha-1 | polymer | 353 | 40283.8 | 1 | UniProt (P63096) Pfam (PF00503) | Homo sapiens (Human) | Adenylate cyclase-inhibiting G alpha protein |
| 2 | B (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 345 | 37728.2 | 1 | UniProt (P62873) Pfam (PF25391) | Homo sapiens (Human) | Transducin beta chain 1 |
| 3 | C (C) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 67 | 7432.6 | 1 | UniProt (P59768) Pfam (PF00631) | Homo sapiens (Human) | G gamma-I |
| 4 | D (D) | Antibody fragment scFv16 | polymer | 256 | 27340.5 | 1 | Mus musculus (mouse) | ||
| 5 | E (R) | BILF1 | polymer | 321 | 35491.9 | 1 | UniProt (Q3KSP2) Pfam (PF25732) UniProt (by SIFTS) (P03208) | Epstein-Barr virus (HHV-4 Human herpesvirus 4) | BILF1 membrane protein,BILF1 protein,G protein-coupled receptor,Membrane protein,Probable membrane protein |
| 6 | F (R) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 1 | Chemie (Y01) |
Sequence modifications
B: 2 - 340 (UniProt: P62873)
R: 1 - 312 (UniProt: Q3KSP2)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Gly 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ala 313 | - | expression tag |
| Ala 314 | - | expression tag |
| Ala 315 | - | expression tag |
| Leu 316 | - | expression tag |
| Glu 317 | - | expression tag |
| Val 318 | - | expression tag |
| Leu 319 | - | expression tag |
| Phe 320 | - | expression tag |
| Gln 321 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 148276.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 486.7 | |
| All* | Total formula weight | 148763.6 |
