7G1V

Crystal Structure of human FABP4 in complex with 3-[(2-sulfanylphenyl)carbamoyl]bicyclo[2.2.1]heptane-2-carboxylic acid, i.e. SMILES [C@@H]1([C@H]2C[C@@H]([C@H]1C(=O)O)CC2)C(=O)Nc1c(cccc1)S with IC50=6.5 microM

Summary for 7G1V

• Entry DOI: 10.2210/pdb7g1v/pdb
• Group deposition: To be published (G_1002264)
• Descriptor: Fatty acid-binding protein, adipocyte, DIMETHYL SULFOXIDE, SULFATE ION, ... (6 entities in total)
• Functional Keywords: lipid binding protein, fatty acid binding protein, cytoplasm, lipid-binding, transport, protein binding
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 15611.81

Authors

Ehler, A.,Benz, J.,Obst, U.,Kumagai, Y.,Rudolph, M.G. (deposition date: 2023-04-27, release date: 2023-06-14, Last modification date: 2024-11-20)

• Primary citation: Obst, U.,Magnone, C.,Kuhn, B.,Rudolph, M.G.; Crystal Structure of a human FABP4 complex; To be published,

Experimental method

X-RAY DIFFRACTION (1.02 Å)