7FE2
Crystal structure of the mutant E494Q of GH92 alpha-1,2-mannosidase from Enterococcus faecalis ATCC 10100 in complex with alpha-1,2-mannobiose
Summary for 7FE2
Entry DOI | 10.2210/pdb7fe2/pdb |
Descriptor | Alpha-1,2-mannosidase, alpha-D-mannopyranose-(1-2)-beta-D-mannopyranose, CALCIUM ION, ... (7 entities in total) |
Functional Keywords | glycoside hydrolase, gh92, inhibitor, carbohydrate, n-glycan, hydrolase |
Biological source | Enterococcus faecalis ATCC 10100 (Streptococcus faecalis) |
Total number of polymer chains | 4 |
Total formula weight | 334285.63 |
Authors | Miyazaki, T.,Alonso-Gil, S. (deposition date: 2021-07-19, release date: 2022-02-02, Last modification date: 2023-11-29) |
Primary citation | Alonso-Gil, S.,Parkan, K.,Kaminsky, J.,Pohl, R.,Miyazaki, T. Unlocking the Hydrolytic Mechanism of GH92 alpha-1,2-Mannosidases: Computation Inspires the use of C-Glycosides as Michaelis Complex Mimics. Chemistry, 28:e202200148-e202200148, 2022 Cited by PubMed: 35049087DOI: 10.1002/chem.202200148 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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