7FE2

Crystal structure of the mutant E494Q of GH92 alpha-1,2-mannosidase from Enterococcus faecalis ATCC 10100 in complex with alpha-1,2-mannobiose

Summary for 7FE2

Entry DOI	10.2210/pdb7fe2/pdb
Descriptor	Alpha-1,2-mannosidase, alpha-D-mannopyranose-(1-2)-beta-D-mannopyranose, CALCIUM ION, ... (7 entities in total)
Functional Keywords	glycoside hydrolase, gh92, inhibitor, carbohydrate, n-glycan, hydrolase
Biological source	Enterococcus faecalis ATCC 10100 (Streptococcus faecalis)
Total number of polymer chains	4
Total formula weight	334285.63
Authors	Miyazaki, T.,Alonso-Gil, S. (deposition date: 2021-07-19, release date: 2022-02-02, Last modification date: 2023-11-29)
Primary citation	Alonso-Gil, S.,Parkan, K.,Kaminsky, J.,Pohl, R.,Miyazaki, T. Unlocking the Hydrolytic Mechanism of GH92 alpha-1,2-Mannosidases: Computation Inspires the use of C-Glycosides as Michaelis Complex Mimics. Chemistry, 28:e202200148-e202200148, 2022 Cited by PubMed: 35049087 DOI: 10.1002/chem.202200148 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75 Å)

Structure validation