7FDV

Cryo-EM structure of the human cholesterol transporter ABCG1 in complex with cholesterol

7FDV の概要

• エントリーDOI: 10.2210/pdb7fdv/pdb
• EMDBエントリー: 31547
• 分子名称: ATP-binding cassette sub-family G member 1, ADENOSINE-5'-TRIPHOSPHATE, [(E,2S,3R)-2-(hexadecanoylamino)-3-oxidanyl-octadec-4-enyl] 2-(trimethylazaniumyl)ethyl phosphate, ... (4 entities in total)
• 機能のキーワード: human abcg1, cholsterol transporter, atp-bound, cholesterol, membrane protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 154535.41

構造登録者

Xu, D.,Li, Y.Y.,Yang, F.R.,Sun, C.R.,Pan, J.H.,Wang, L.,Chen, Z.P.,Fang, S.C.,Yao, X.B.,Hou, W.T.,Zhou, C.Z.,Chen, Y. (登録日: 2021-07-18, 公開日: 2022-06-22, 最終更新日: 2024-06-12)

• 主引用文献: Xu, D.,Li, Y.,Yang, F.,Sun, C.R.,Pan, J.,Wang, L.,Chen, Z.P.,Fang, S.C.,Yao, X.,Hou, W.T.,Zhou, C.Z.,Chen, Y.; Structure and transport mechanism of the human cholesterol transporter ABCG1.; Cell Rep, 38:110298-110298, 2022; PubMed: 35081353; DOI: 10.1016/j.celrep.2022.110298

実験手法

ELECTRON MICROSCOPY (3.26 Å)