7F2J

Crystal structure of AtFKBP53 FKBD in complex with rapamycin

Summary for 7F2J

• Entry DOI: 10.2210/pdb7f2j/pdb
• Related: 6J2M
• Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP53, RAPAMYCIN IMMUNOSUPPRESSANT DRUG, SULFATE ION, ... (5 entities in total)
• Functional Keywords: fkbp, rapamycin, dimerization, isomerase
• Biological source: Arabidopsis thaliana (Mouse-ear cress)
• Total number of polymer chains: 2
• Total formula weight: 29712.25

Authors

Singh, A.K.,Saharan, K.,Vasudevan, D. (deposition date: 2021-06-11, release date: 2022-03-09, Last modification date: 2023-11-29)

• Primary citation: Singh, A.K.,Saharan, K.,Baral, S.,Luan, S.,Vasudevan, D.; Crystal packing reveals rapamycin-mediated homodimerization of an FK506-binding domain.; Int.J.Biol.Macromol., 206:670-680, 2022; PubMed: 35218805; DOI: 10.1016/j.ijbiomac.2022.02.107

Experimental method

X-RAY DIFFRACTION (1.6 Å)