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7F2J

Crystal structure of AtFKBP53 FKBD in complex with rapamycin

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Peptidyl-prolyl cis-trans isomerase FKBP53polymer12413648.72UniProt (Q93ZG9)
Pfam (PF00254)
Arabidopsis thaliana (Mouse-ear cress)PPIase FKBP53,FK506-binding protein 53,AtFKBP53,Immunophilin FKBP53,Rotamase
2C, H
(A, B)
RAPAMYCIN IMMUNOSUPPRESSANT DRUGnon-polymer914.22Chemie (RAP)
3D, E, F, G, I
(A, B)
SULFATE IONnon-polymer96.15Chemie (SO4)
4J
(B)
DI(HYDROXYETHYL)ETHERnon-polymer106.11Chemie (PEG)
5K, L
(A, B)
waterwater18.085Chemie (HOH)
Sequence modifications
A, B: 362 - 477 (UniProt: Q93ZG9)
PDBExternal DatabaseDetails
Leu 478-expression tag
Glu 479-expression tag
His 480-expression tag
His 481-expression tag
His 482-expression tag
His 483-expression tag
His 484-expression tag
His 485-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight27297.5
Non-Polymers*Number of molecules8
Total formula weight2414.8
All*Total formula weight29712.3
*Water molecules are not included.

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PDB entries from 2025-07-02

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