7F0F

Crystal structure of capreomycin phosphotransferase in complex with CMN IIB

Summary for 7F0F

• Entry DOI: 10.2210/pdb7f0f/pdb
• Related PRD ID: PRD_002272
• Descriptor: Capreomycin phosphotransferase, DPP-ALA-DPP-UAL-MYN-KBE (3 entities in total)
• Functional Keywords: cph, phosphotransferase, capreomycin, resistance, transferase
• Biological source: Saccharothrix mutabilis subsp. capreolus (Streptomyces capreolus); More
• Total number of polymer chains: 2
• Total formula weight: 32107.18

Authors

Chang, C.Y.,Pan, Y.C.,Wang, Y.L.,Toh, S.I. (deposition date: 2021-06-03, release date: 2022-05-11, Last modification date: 2023-11-29)

• Primary citation: Pan, Y.C.,Wang, Y.L.,Toh, S.I.,Hsu, N.S.,Lin, K.H.,Xu, Z.,Huang, S.C.,Wu, T.K.,Li, T.L.,Chang, C.Y.; Dual-Mechanism Confers Self-Resistance to the Antituberculosis Antibiotic Capreomycin.; Acs Chem.Biol., 17:138-146, 2022; PubMed: 34994196; DOI: 10.1021/acschembio.1c00799

Experimental method

X-RAY DIFFRACTION (2.1 Å)