7EQ2

Crystal structure of GDP-bound Rab1a-T75D

7EQ2 の概要

• エントリーDOI: 10.2210/pdb7eq2/pdb
• 分子名称: Ras-related protein Rab-1A, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (7 entities in total)
• 機能のキーワード: ras-related protein rab-1a, small gtpase, protein trafficking, signal transduction, membrane remolding, cell cycle
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 44315.55

構造登録者

Cao, Y.L.,Gu, D.D.,Gao, S. (登録日: 2021-04-28, 公開日: 2022-11-02, 最終更新日: 2024-01-10)

• 主引用文献: Zhang, W.,Zhang, Z.,Xiang, Y.,Gu, D.D.,Chen, J.,Chen, Y.,Zhai, S.,Liu, Y.,Jiang, T.,Liu, C.,He, B.,Yan, M.,Wang, Z.,Xu, J.,Cao, Y.L.,Deng, B.,Zeng, D.,Lei, J.,Zhuo, J.,Lei, X.,Long, Z.,Jin, B.,Chen, T.,Li, D.,Shen, Y.,Hu, J.,Gao, S.,Liu, Q.; Aurora kinase A-mediated phosphorylation triggers structural alteration of Rab1A to enhance ER complexity during mitosis; Nat.Struct.Mol.Biol., 2024; DOI: 10.1038/s41594-023-01165-7

実験手法

X-RAY DIFFRACTION (1.55090284637 Å)