7EPT
Structural basis for the tethered peptide activation of adhesion GPCRs
Summary for 7EPT
Entry DOI | 10.2210/pdb7ept/pdb |
EMDB information | 31232 |
Descriptor | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total) |
Functional Keywords | adhesion gpcr, gpr133, structural protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 5 |
Total formula weight | 138316.35 |
Authors | Ping, Y.-Q.,Xiao, P.,Yang, F.,Zhao, R.-J.,Guo, S.-C.,Yan, X.,Wu, X.,Liebscher, I.,Xu, H.E.,Sun, J.-P. (deposition date: 2021-04-27, release date: 2022-05-11) |
Primary citation | Ping, Y.Q.,Xiao, P.,Yang, F.,Zhao, R.J.,Guo, S.C.,Yan, X.,Wu, X.,Zhang, C.,Lu, Y.,Zhao, F.,Zhou, F.,Xi, Y.T.,Yin, W.,Liu, F.Z.,He, D.F.,Zhang, D.L.,Zhu, Z.L.,Jiang, Y.,Du, L.,Feng, S.Q.,Schoneberg, T.,Liebscher, I.,Xu, H.E.,Sun, J.P. Structural basis for the tethered peptide activation of adhesion GPCRs. Nature, 604:763-770, 2022 Cited by PubMed: 35418678DOI: 10.1038/s41586-022-04619-y PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3 Å) |
Structure validation
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