7EOB

Crystal structure of KIF1A Motor-Neck domain E239K mutant with ADP-Mg-AlFx

Summary for 7EOB

Entry DOI	10.2210/pdb7eob/pdb
Descriptor	Kinesin-like protein KIF1A, ALUMINUM FLUORIDE, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	kinesin, motor protein
Biological source	Mus musculus (Mouse)
Total number of polymer chains	1
Total formula weight	44508.03
Authors	Ogawa, T.,Jiang, X.,Hirokawa, N. (deposition date: 2021-04-21, release date: 2021-12-29, Last modification date: 2023-11-29)
Primary citation	Morikawa, M.,Jerath, N.U.,Ogawa, T.,Morikawa, M.,Tanaka, Y.,Shy, M.E.,Zuchner, S.,Hirokawa, N. A neuropathy-associated kinesin KIF1A mutation hyper-stabilizes the motor-neck interaction during the ATPase cycle. Embo J., 41:e108899-e108899, 2022 Cited by PubMed: 35132656 DOI: 10.15252/embj.2021108899 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.76 Å)

Structure validation