7EOB

Crystal structure of KIF1A Motor-Neck domain E239K mutant with ADP-Mg-AlFx

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003777	molecular_function	microtubule motor activity
A	0005524	molecular_function	ATP binding
A	0007018	biological_process	microtubule-based movement
A	0008017	molecular_function	microtubule binding

Functional Information from PROSITE/UniProt

site_id	PS00411
Number of Residues	12
Details	KINESIN_MOTOR_1 Kinesin motor domain signature. SKIsLVDLAGSE

Chain	Residue	Details
A	SER242-GLU253

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:18806800, ECO:0000269|PubMed:35132656, ECO:0000305|PubMed:15286375, ECO:0007744|PDB:1VFX, ECO:0007744|PDB:1VFZ, ECO:0007744|PDB:2ZFI, ECO:0007744|PDB:2ZFJ, ECO:0007744|PDB:2ZFK, ECO:0007744|PDB:2ZFL, ECO:0007744|PDB:2ZFM, ECO:0007744|PDB:7EO9, ECO:0007744|PDB:7EOB

Chain	Residue	Details
A	TYR67

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site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:18806800, ECO:0000269|PubMed:35132656, ECO:0000305|PubMed:15286375, ECO:0007744|PDB:1VFX, ECO:0007744|PDB:1VFZ, ECO:0007744|PDB:2ZFI, ECO:0007744|PDB:2ZFK, ECO:0007744|PDB:2ZFL, ECO:0007744|PDB:2ZFM, ECO:0007744|PDB:7EO9, ECO:0007744|PDB:7EOB

Chain	Residue	Details
A	GLY100

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site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:18806800, ECO:0000269|PubMed:35132656, ECO:0000305|PubMed:15286375, ECO:0007744|PDB:1VFX, ECO:0007744|PDB:2ZFJ, ECO:0007744|PDB:2ZFK, ECO:0007744|PDB:2ZFL, ECO:0007744|PDB:2ZFM, ECO:0007744|PDB:7EO9

Chain	Residue	Details
A	ALA101

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site_id	SWS_FT_FI4
Number of Residues	4
Details	BINDING: BINDING => ECO:0000305|PubMed:15286375, ECO:0007744|PDB:1VFV, ECO:0007744|PDB:1VFW

Chain	Residue	Details
A	GLY102
A	LYS103
A	TYR105
A	SER215

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site_id	SWS_FT_FI5
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:15286375, ECO:0000269|PubMed:18806800, ECO:0000269|PubMed:35132656, ECO:0007744|PDB:1VFV, ECO:0007744|PDB:1VFW, ECO:0007744|PDB:1VFX, ECO:0007744|PDB:1VFZ, ECO:0007744|PDB:2ZFI, ECO:0007744|PDB:2ZFK, ECO:0007744|PDB:7EO9, ECO:0007744|PDB:7EOB

Chain	Residue	Details
A	SER104

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