7EOB

Crystal structure of KIF1A Motor-Neck domain E239K mutant with ADP-Mg-AlFx

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003777	molecular_function	microtubule motor activity
A	0005524	molecular_function	ATP binding
A	0007018	biological_process	microtubule-based movement
A	0008017	molecular_function	microtubule binding

Functional Information from PROSITE/UniProt

site_id	PS00411
Number of Residues	12
Details	KINESIN_MOTOR_1 Kinesin motor domain signature. SKIsLVDLAGSE

Chain	Residue	Details
A	SER242-GLU253

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18806800","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35132656","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15286375","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1VFX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1VFZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZFI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZFJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZFK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZFL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZFM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7EO9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7EOB","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18806800","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35132656","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15286375","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1VFX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1VFZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZFI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZFK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZFL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZFM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7EO9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7EOB","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18806800","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35132656","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15286375","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1VFX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZFJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZFK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZFL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZFM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7EO9","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15286375","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1VFV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1VFW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15286375","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18806800","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35132656","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1VFV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1VFW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1VFX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1VFZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZFI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZFK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7EO9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7EOB","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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