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7EEU

Human p53 core domain with hot spot mutation R282W in complex with the natural CDKN1A(p21) p53-response element and Arsenic

Summary for 7EEU
Entry DOI10.2210/pdb7eeu/pdb
DescriptorCellular tumor antigen p53, CDKN1A(p21) sense strand, CDKN1A(p21) anti-sense strand, ... (7 entities in total)
Functional Keywordsdna-binding domain, complex, dna-bound, arsenic-bound, transcription
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains12
Total formula weight218507.44
Authors
Xing, Y.F.,Lu, M. (deposition date: 2021-03-19, release date: 2022-06-22, Last modification date: 2023-11-29)
Primary citationXing, Y.F.,Lu, M.
Human p53 core domain with hot spot mutation R282W in complex with the natural CDKN1A(p21) p53-response element and Arsenic
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.9 Å)
Structure validation

221051

건을2024-06-12부터공개중

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