7E9B

Structural basis of HLX10 PD-1 receptor recognition, a promising anti-PD-1 antibody clinical candidate for cancer immunotherapy

7E9B の概要

• エントリーDOI: 10.2210/pdb7e9b/pdb
• 分子名称: heavy chain of Fab fragment of HLX10, light chain of Fab fragment of HLX10, Programmed cell death protein 1, ... (4 entities in total)
• 機能のキーワード: antibody, mab, pd-1, pd-l-1, cancer, t-cell, immunotherapy, ici, immune system
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 59205.97

構造登録者

Fan, S.L.,Jiang, W.D. (登録日: 2021-03-04, 公開日: 2021-07-28, 最終更新日: 2023-11-29)

• 主引用文献: Issafras, H.,Fan, S.,Tseng, C.L.,Cheng, Y.,Lin, P.,Xiao, L.,Huang, Y.J.,Tu, C.H.,Hsiao, Y.C.,Li, M.,Chen, Y.H.,Ho, C.H.,Li, O.,Wang, Y.,Chen, S.,Ji, Z.,Zhang, E.,Mao, Y.T.,Liu, E.,Yang, S.,Jiang, W.; Structural basis of HLX10 PD-1 receptor recognition, a promising anti-PD-1 antibody clinical candidate for cancer immunotherapy.; Plos One, 16:e0257972-e0257972, 2021; PubMed: 34972111; DOI: 10.1371/journal.pone.0257972

実験手法

X-RAY DIFFRACTION (1.78 Å)