7E8M

Crystal structure of SARS-CoV-2 antibody P2C-1F11 with mutated RBD

7E8M の概要

• エントリーDOI: 10.2210/pdb7e8m/pdb
• 分子名称: Spike protein S1, antibody P2C-1F11 heavy chain, antibody P2C-1F11 light chain, ... (5 entities in total)
• 機能のキーワード: sars-cov-2 spike, receptor binding domain, antibody, viral protein, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 68255.12

構造登録者

Wang, X.Q.,Zhang, L.Q.,Ge, J.W.,Wang, R.K.,Lan, J. (登録日: 2021-03-02, 公開日: 2021-05-26, 最終更新日: 2023-11-29)

• 主引用文献: Wang, R.,Zhang, Q.,Ge, J.,Ren, W.,Zhang, R.,Lan, J.,Ju, B.,Su, B.,Yu, F.,Chen, P.,Liao, H.,Feng, Y.,Li, X.,Shi, X.,Zhang, Z.,Zhang, F.,Ding, Q.,Zhang, T.,Wang, X.,Zhang, L.; Analysis of SARS-CoV-2 variant mutations reveals neutralization escape mechanisms and the ability to use ACE2 receptors from additional species.; Immunity, 54:1611-1621.e5, 2021; PubMed: 34166623; DOI: 10.1016/j.immuni.2021.06.003

実験手法

X-RAY DIFFRACTION (2.09 Å)