7E6E
Crystal structure of PMP-bound form of cysteine desulfurase SufS R376A from Bacillus subtilis in D-cycloserine-inhibition
Summary for 7E6E
Entry DOI | 10.2210/pdb7e6e/pdb |
Descriptor | Cysteine desulfurase SufS, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, TETRAETHYLENE GLYCOL, ... (6 entities in total) |
Functional Keywords | cysteine desulfurase, plp-dependent enzyme, cysteine metabolism, cycloserine, inhibitor, fe-s cluster biosynthesis, biosynthetic protein |
Biological source | Bacillus subtilis subsp. subtilis str. 168 |
Total number of polymer chains | 1 |
Total formula weight | 47739.75 |
Authors | Nakamura, R.,Takahashi, Y.,Fujishiro, T. (deposition date: 2021-02-22, release date: 2022-03-02, Last modification date: 2023-11-29) |
Primary citation | Nakamura, R.,Ogawa, S.,Takahashi, Y.,Fujishiro, T. Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms. Febs J., 289:5947-5970, 2022 Cited by PubMed: 35395703DOI: 10.1111/febs.16455 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.28 Å) |
Structure validation
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