7E6E

Crystal structure of PMP-bound form of cysteine desulfurase SufS R376A from Bacillus subtilis in D-cycloserine-inhibition

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Cysteine desulfurase SufS	polymer	419	46500.5	1	UniProt (O32164) Pfam (PF00266) In PDB	Bacillus subtilis subsp. subtilis str. 168
2	A	4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE	non-polymer		248.2	1	Chemie (PMP)
3	A	TETRAETHYLENE GLYCOL	non-polymer		194.2	1	Chemie (PG4)
4	A	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	4	Chemie (PEG)
5	A	1,2-ETHANEDIOL	non-polymer		62.1	6	Chemie (EDO)
6		water	water		18.0	95	Chemie (HOH)

Sequence modifications

A: 1 - 406 (UniProt: O32164)

PDB	External Database	Details
Met -2	-	initiating methionine
Gly -1	-	expression tag
His 0	-	expression tag
Ala 376	Arg 376	engineered mutation
Val 407	-	expression tag
Asp 408	-	expression tag
Leu 409	-	expression tag
Glu 410	-	expression tag
His 411	-	expression tag
His 412	-	expression tag
His 413	-	expression tag
His 414	-	expression tag
His 415	-	expression tag
His 416	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	46500.5
Non-Polymers*	Number of molecules	12
	Total formula weight	1239.3
All*	Total formula weight	47739.8

*Water molecules are not included.