7DU9

Crystal structure of human Proto-oncogene tyrosine-protein kinase receptor Ret in complex with Pralsetinib

Summary for 7DU9

• Entry DOI: 10.2210/pdb7du9/pdb
• Descriptor: Proto-oncogene tyrosine-protein kinase receptor Ret, Pralsetinib (3 entities in total)
• Functional Keywords: tyrosine-protein kinase, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 72483.67

Authors

Miyazaki, I.,Ishida, K.,Suzuki, T. (deposition date: 2021-01-08, release date: 2022-01-12, Last modification date: 2024-05-29)

• Primary citation: Miyazaki, I.,Ishida, K.,Suzuki, T.; Selective RET inhibitor TAS0953/HM06; To be published,

Experimental method

X-RAY DIFFRACTION (2.31 Å)