7DSX
Structure of a human NHE1-CHP1 complex under pH 7.5, bound by cariporide
Summary for 7DSX
Entry DOI | 10.2210/pdb7dsx/pdb |
EMDB information | 30849 |
Descriptor | Calcineurin B homologous protein 1, Sodium/hydrogen exchanger 1, (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, ... (4 entities in total) |
Functional Keywords | transporter, membrane protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 162013.22 |
Authors | Dong, Y.,Gao, Y.,Li, B.,Zhang, X.C.,Zhao, Y. (deposition date: 2021-01-03, release date: 2021-06-23, Last modification date: 2024-03-27) |
Primary citation | Dong, Y.,Gao, Y.,Ilie, A.,Kim, D.,Boucher, A.,Li, B.,Zhang, X.C.,Orlowski, J.,Zhao, Y. Structure and mechanism of the human NHE1-CHP1 complex. Nat Commun, 12:3474-3474, 2021 Cited by PubMed: 34108458DOI: 10.1038/s41467-021-23496-z PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.5 Å) |
Structure validation
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