7DKM
PHGDH covalently linked to oridonin
Summary for 7DKM
Entry DOI | 10.2210/pdb7dkm/pdb |
Descriptor | D-3-phosphoglycerate dehydrogenase, (1beta,6beta,7beta,8alpha,9beta,10alpha,13alpha,14R,16beta)-1,6,7,14-tetrahydroxy-7,20-epoxykauran-15-one, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (7 entities in total) |
Functional Keywords | inhibitor, complex, dehydrogenase, covalent, oxidoreductase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 69967.63 |
Authors | |
Primary citation | Tan, Y.,Zhou, X.,Gong, Y.,Gou, K.,Luo, Y.,Jia, D.,Dai, L.,Zhao, Y.,Sun, Q. Biophysical and biochemical properties of PHGDH revealed by studies on PHGDH inhibitors. Cell.Mol.Life Sci., 79:27-27, 2021 Cited by PubMed: 34971423DOI: 10.1007/s00018-021-04022-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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