7DK1
Crystal structure of Zinc bound SARS-CoV-2 main protease
Summary for 7DK1
Entry DOI | 10.2210/pdb7dk1/pdb |
Descriptor | 3C-like proteinase, ZINC ION, DIMETHYL SULFOXIDE, ... (7 entities in total) |
Functional Keywords | sars-cov-2, main protease, zinc, mpro-zinc complex, peptide binding protein, hydrolase |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) |
Total number of polymer chains | 2 |
Total formula weight | 68476.55 |
Authors | Sonkar, K.S.,Panchariya, L.,Kuila, S.,Khan, W.A.,Arockiasamy, A. (deposition date: 2020-11-22, release date: 2021-06-30, Last modification date: 2023-11-29) |
Primary citation | Panchariya, L.,Khan, W.A.,Kuila, S.,Sonkar, K.,Sahoo, S.,Ghoshal, A.,Kumar, A.,Verma, D.K.,Hasan, A.,Khan, M.A.,Jain, N.,Mohapatra, A.K.,Das, S.,Thakur, J.K.,Maiti, S.,Nanda, R.K.,Halder, R.,Sunil, S.,Arockiasamy, A. Zinc 2+ ion inhibits SARS-CoV-2 main protease and viral replication in vitro. Chem.Commun.(Camb.), 57:10083-10086, 2021 Cited by PubMed: 34514483DOI: 10.1039/d1cc03563k PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.902 Å) |
Structure validation
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