7DHA

crystal structure of CD38 in complex with daratumumab

Summary for 7DHA

• Entry DOI: 10.2210/pdb7dha/pdb
• Descriptor: ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, Light chain, Heavy Chain, ... (4 entities in total)
• Functional Keywords: cd38, antibody, daratumumab, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 79130.75

Authors

Lee, H.T.,Heo, Y.S. (deposition date: 2020-11-13, release date: 2021-09-22, Last modification date: 2023-11-29)

• Primary citation: Lee, H.T.,Kim, Y.,Park, U.B.,Jeong, T.J.,Lee, S.H.,Heo, Y.S.; Crystal structure of CD38 in complex with daratumumab, a first-in-class anti-CD38 antibody drug for treating multiple myeloma.; Biochem.Biophys.Res.Commun., 536:26-31, 2021; PubMed: 33360095; DOI: 10.1016/j.bbrc.2020.12.048

Experimental method

X-RAY DIFFRACTION (2.55 Å)