7CT5
S protein of SARS-CoV-2 in complex bound with T-ACE2
Summary for 7CT5
Entry DOI | 10.2210/pdb7ct5/pdb |
EMDB information | 30460 30461 |
Descriptor | Spike glycoprotein, Angiotensin-converting enzyme 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | s-ecd, ace2, viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) More |
Total number of polymer chains | 6 |
Total formula weight | 674913.50 |
Authors | Guo, L.,Bi, W.W.,Zhang, Y.Y.,Yan, R.H.,Li, Y.N.,Zhou, Q.,Dang, B.B. (deposition date: 2020-08-18, release date: 2020-11-18, Last modification date: 2021-02-10) |
Primary citation | Guo, L.,Bi, W.,Wang, X.,Xu, W.,Yan, R.,Zhang, Y.,Zhao, K.,Li, Y.,Zhang, M.,Cai, X.,Jiang, S.,Xie, Y.,Zhou, Q.,Lu, L.,Dang, B. Engineered trimeric ACE2 binds viral spike protein and locks it in "Three-up" conformation to potently inhibit SARS-CoV-2 infection. Cell Res., 31:98-100, 2021 Cited by PubMed: 33177651DOI: 10.1038/s41422-020-00438-w PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4 Å) |
Structure validation
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