7CMS

Crystal structure of Tryptophanyl-tRNA synthetase from Bacillus stearothermophilus in complex with chuangxinmycin

7CMS の概要

• エントリーDOI: 10.2210/pdb7cms/pdb
• 分子名称: Tryptophan--tRNA ligase, (5~{S},6~{R})-5-methyl-7-thia-2-azatricyclo[6.3.1.0^{4,12}]dodeca-1(12),3,8,10-tetraene-6-carboxylic acid, PHOSPHATE ION, ... (4 entities in total)
• 機能のキーワード: chuangxinmycin, antibiotic
• 由来する生物種: Geobacillus stearothermophilus
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 75107.86

構造登録者

Lyu, G.,Fan, S.,Jin, Y.,Zou, S.,Wu, G.,Yang, Z. (登録日: 2020-07-28, 公開日: 2021-08-04, 最終更新日: 2023-11-29)

• 主引用文献: Fan, S.,Lv, G.,Feng, X.,Wu, G.,Jin, Y.,Yan, M.,Yang, Z.; Structural insights into the specific interaction between Geobacillus stearothermophilus tryptophanyl-tRNA synthetase and antimicrobial Chuangxinmycin.; J.Biol.Chem., 298:101580-, 2022; DOI: 10.1016/j.jbc.2022.101580

実験手法

X-RAY DIFFRACTION (2.2 Å)