7CHZ

Crystal Structure Of Human Il-1beta In Complex With Antibody Binding Fragment Of IgG26A

7CHZ の概要

• エントリーDOI: 10.2210/pdb7chz/pdb
• 分子名称: light chain of antibody binding fragment of IgG26A, heavy chain of antibody binding fragment of IgG26A, Interleukin-1 beta, ... (4 entities in total)
• 機能のキーワード: complex, antibody, interleukin-1beta, immunosuppressant
• 由来する生物種: Homo sapiens; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 65595.66

構造登録者

Lee, C.C.,Wang, A.H.J.,Kuo, W.C. (登録日: 2020-07-06, 公開日: 2021-01-13, 最終更新日: 2023-11-29)

• 主引用文献: Kuo, W.C.,Lee, C.C.,Chang, Y.W.,Pang, W.,Chen, H.S.,Hou, S.C.,Lo, S.Y.,Yang, A.S.,Wang, A.H.; Structure-based Development of Human Interleukin-1 beta-Specific Antibody That Simultaneously Inhibits Binding to Both IL-1RI and IL-1RAcP.; J.Mol.Biol., 433:166766-166766, 2020; PubMed: 33359099; DOI: 10.1016/j.jmb.2020.166766

実験手法

X-RAY DIFFRACTION (2.5 Å)