7CD5
mAPE1-blunt-ended dsDNA product complex
Summary for 7CD5
Entry DOI | 10.2210/pdb7cd5/pdb |
Descriptor | DNA(5'-D(*CP*GP*TP*AP*AP*TP*AP*CP*G)-3'), DNA-(apurinic or apyrimidinic site) endonuclease (2 entities in total) |
Functional Keywords | ape1, protein-nucleic acid interaction, exonuclease, dna repair, dna binding protein, hydrolase-dna complex, hydrolase/dna |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 2 |
Total formula weight | 41835.16 |
Authors | Liu, T.C.,Hsiao, Y.Y. (deposition date: 2020-06-18, release date: 2021-01-13, Last modification date: 2023-11-29) |
Primary citation | Liu, T.C.,Lin, C.T.,Chang, K.C.,Guo, K.W.,Wang, S.,Chu, J.W.,Hsiao, Y.Y. APE1 distinguishes DNA substrates in exonucleolytic cleavage by induced space-filling. Nat Commun, 12:601-601, 2021 Cited by PubMed: 33504804DOI: 10.1038/s41467-020-20853-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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