7CBY

Structure of FOXG1 DNA binding domain bound to DBE2 DNA site

Summary for 7CBY

• Entry DOI: 10.2210/pdb7cby/pdb
• Descriptor: DNA (5'-D(*TP*CP*TP*TP*GP*TP*TP*TP*AP*CP*AP*TP*TP*TP*TP*G)-3'), DNA (5'-D(*CP*AP*AP*AP*AP*TP*GP*TP*AP*AP*AP*CP*AP*AP*GP*A)-3'), Forkhead box protein G1, ... (5 entities in total)
• Functional Keywords: foxg1, forkhead box, transcription factors, foxg1 syndrome, dbe2, transcription
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 22383.83

Authors

Dai, S.Y.,Li, J.,Chen, Y.H. (deposition date: 2020-06-15, release date: 2020-10-28, Last modification date: 2023-11-29)

• Primary citation: Dai, S.,Li, J.,Zhang, H.,Chen, X.,Guo, M.,Chen, Z.,Chen, Y.; Structural Basis for DNA Recognition by FOXG1 and the Characterization of Disease-causing FOXG1 Mutations.; J.Mol.Biol., 432:6146-6156, 2020; PubMed: 33058871; DOI: 10.1016/j.jmb.2020.10.007

Experimental method

X-RAY DIFFRACTION (1.646 Å)